Frusemide

Overview

What is Frusemide?   

Frusemide, also known as furosemide, is a potent diuretic medication used primarily to treat fluid build-up due to heart failure, liver scarring, or kidney disease and as maintenance medication for hypertension. It helps eliminate excess fluid from the body by increasing urine production, which aids in reducing symptoms such as swelling and fluid retention. 

Frusemide is a loop diuretic, which means it works on the Loop of Henle in the kidney to prevent the absorption of sodium and chloride, effectively increasing the amount of salt and water expelled from the body. 

Global Name

• Generic name: Furosemide 
• Brand names: Lasix, Frumil, Frusenex. 

Usage

What is Frusemide used for? 

Frusemide is used to treat several conditions, including: 

• Edema (fluid retention) associated with heart failure, liver cirrhosis, and renal disease 
• Hypertension (high blood pressure) 
• Certain cases of hypercalcemia (high calcium levels in the blood) 

How do you use Frusemide? 

Availability:

Frusemide is available in tablet, liquid, and injectable forms.

Dosage information:

• Adults: For edema, initial doses range from 20 mg to 80 mg per day. For hypertension, 40 mg twice daily initially, or as directed by a physician. 
• Children: Doses are based on body weight, generally 1-2 mg/kg body weight once or twice a day. 

Are the following suitable to take the drug: Children, adults, elderlies? 

• Children: Yes, under medical supervision 
• Adults: Yes 
• Elderlies: Yes, dose adjustment may be necessary 
• Pregnancy: Use only if necessary and under medical supervision 
• Lactation: Not recommended as it passes into breast milk 

Is there anyone who can’t take Frusemide? 

• Children: Safe under medical supervision 
• Adults: Those with anuria, severe electrolyte imbalances 
• Elderlies: Caution advised, especially with dose adjustments 
• Pregnancy: Use advised against unless absolutely necessary 
• Lactation: Generally not recommended 

Allergies: Individuals allergic to sulfonylureas or sulfonamides may also be allergic to frusemide. 

Warnings and Precautions:

• Monitor electrolytes and kidney function regularly. 
• Can lead to dehydration and electrolyte depletion. 
• Take early in the day to avoid nocturia (nighttime urination). 

Drug and Food/Beverage Interactions: 

• Avoid taking with aminoglycoside antibiotics (risk of ototoxicity/hearing damage). 
• NSAIDs can reduce the effectiveness of frusemide and increase renal (kidney) toxicity. 
• Increases the risk of lithium toxicity when used concurrently.

Side Effects

Common side effects include dehydration, electrolyte imbalance, hypotension, light-headedness, and gastrointestinal disturbances. 

Pharmacist Tips

Storage information: 

• Store at room temperature away from moisture and heat. 

Handling instructions: 

• Keep track of your medication intake to avoid missing doses. 

• Monitor your blood pressure and electrolyte levels regularly. 

Availability

Where is Frusemide available in Hong Kong?

Frusemide is a prescription medication that can be prescribed by healthcare providers. 

FAQs

How quickly does Frusemide work? 

Frusemide acts within an hour when taken orally, and its effects last for approximately 6 to 8 hours.

Can I take Frusemide at night? 

It is recommended to take Frusemide in the morning to avoid disturbing sleep with frequent urination. 

What should I do if I miss a dose? 

Take the missed dose as soon as you remember unless it's close to the time for your next dose. Do not double up doses.

Can I drink alcohol while taking Frusemide? 

Alcohol can increase the risk of side effects from frusemide, such as dizziness and dehydration. It’s best to limit or avoid alcohol. 

This guide serves to provide comprehensive information on Frusemide, assisting patients in managing conditions associated with fluid retention and hypertension effectively.