Miconazole

Overview

What is Miconazole?   

Miconazole is an antifungal medication widely used to combat fungal skin infections such as athlete's foot, ringworm, and yeast infections. It functions by disrupting the production of ergosterol, a vital component of fungal cell membranes, thereby damaging the fungal cells and stopping their growth and reproduction. 

Miconazole is a synthetic imidazole antifungal agent. It interferes with the synthesis of ergosterol through inhibition of the enzyme lanosterol demethylase, crucial for fungal cell membrane formation and function. 

Global Name

• Generic name: Miconazole
• Brand names: Daktarin, Monistat, Micatin, Miconaz, Dermazole, among others 

Usage

What is Miconazole used for? 

Miconazole is employed in the treatment of various fungal infections, including: 

• Athlete's foot (tinea pedis) 

• Jock itch (tinea cruris) 

• Ringworm (tinea corporis) 

• Vaginal yeast infections (vaginal candidiasis) 

• Oral thrush (oral candidiasis) 

How do you use Miconazole? 

Availability: 

 Miconazole is available in cream, powder, spray, and suppository/ pessary forms. 

Dosage information: 

• Cream/Powder/Spray:  

• Adults and Children: Apply to the affected area once or twice daily for 2 to 4 weeks, depending on the severity of the infection. 

• Vaginal Suppositories:  

• Adults: Insert one suppository into the vagina, usually at bedtime for 3 to 7 days, depending on the product formulation. 

• Oral Gel:  

• Adults and Children: Apply to the affected area in the mouth 4 times per day for 1-2 weeks. 

Are the following suitable to take Miconazole: Children, adults, elderlies? 

• Children: Yes, under medical supervision. 

• Adults: Suitable for adults. 

• Elderlies: No specific contraindications, suitable for use under general guidelines. 

Is there anyone who can’t take Miconazole? 

• Children: Not recommended for infants without a doctor’s advice. 

• Adults: Avoid if allergic to miconazole or other azole antifungal agents. 

• Elderlies: No specific restrictions, but as with all medications, use with caution. 

• Pregnancy: Generally considered safe but should be used only under medical advice. 

• Lactation: Consult a healthcare provider before use. 

Allergies: Avoid if known allergies to miconazole or azole antifungals and excipients are present. 

Warnings and precautions: For external use only, unless it is a vaginal product. Avoid contact with eyes. 

Interactions and contraindications of the drug: 

• Interacts with: Warfarin and other oral anticoagulants, increasing their effects. 

• Conditions: Not to be used in patients with liver dysfunction without consulting a doctor. 

Side Effects

Some potential side effects include: 

• Itching 

• Redness 

• Irritation at the application site 
  

Pharmacist Tips

Availability

Where is Miconazole available in Hong Kong?

Miconazole is an over-the-counter (OTC) medication that can be sold without a prescription. It is available in all chain drug stores, including Mannings and Watsons. 

FAQs

Can Miconazole be used daily? 

Yes, follow the prescribed schedule typically once or twice daily until the course is complete to prevent recurrence. 

Is Miconazole safe for kids? 

Yes, but parental supervision and doctor’s advice are recommended for children’s treatment. 

How long does it take for Miconazole to work? 

Improvement is often seen within a few days, but the full course should be completed as directed. 

Can Miconazole treat nail fungus? 

Miconazole is generally used for skin and yeast infections. Nail fungus often requires specific types of treatment.