Retinoic Acid

Overview

What is Retinoic Acid?   

Retinoic Acid, also known as Tretinoin, is a potent derivative of vitamin A. It is primarily used in dermatology for its powerful effects on skin cell growth and development. This compound helps in the modulation of cell proliferation and differentiation, making it a key ingredient in the treatment of various skin conditions. 

Retinoic Acid is synthesized from vitamin A. The process involves the oxidation of retinol (vitamin A alcohol), which then becomes retinaldehyde before finally being converted to Retinoic Acid. This biochemical transformation allows Retinoic Acid to interact directly with nuclear receptors in the skin cells. 

Global Name

• Topical form: Retin-A, Renova, Avita, Refissa,  
• Oral form: Vesanoid 

Usage

What is Retinoic Acid used for? 

Retinoic Acid is used to treat a range of skin conditions. These include: 

• Acne 
• Photoaging (premature aging of the skin due to sun exposure) 
• Acute promyelocytic leukemia (as a chemotherapeutic agent) 
• Keratosis pilaris 

How do you use Retinoic Acid? 

Availability:

Retinoic Acid is available in various forms including creams, gels, and capsules.

Dosage information:

• Adults and Elderlies: Apply a pea-sized amount of cream or gel to the affected area once a day at bedtime. 

• Children: Use is not recommended for children under 12 unless directed by a healthcare provider. 

Are the following suitable to take the drug: Children, adults, elderlies? 

• Adults: Suitable for adults. 
• Elderlies: Can be used with caution, monitoring for skin sensitivity. 
• Lactation: Oral form not generally recommended as it can pass into breast milk. 
  

• • Children: Not recommended under 12 years. 
  • Pregnancy: Not recommended due to potential risk of harm to the fetus (teratogenicity). 
  • Nursing mothers: Intake of the oral form is generally not recommended for breastfeeding mothers. The topical preparation may be used under medical advice and supervision. 

Warnings and Precautions:

Drug and Food/Beverage Interactions: 

Side Effects

Common side effects include redness, peeling, and dryness of the skin. More severe reactions may include blistering and skin discoloration. 

Pharmacist Tips

Storage information: 
Store at room temperature away from light and moisture. Do not freeze the medication. 

Handling instructions: 
Wash hands before and after applying Retinoic Acid. Do not apply near the eyes or open wounds. 

Availability

Where is Retinoic Acid available in Hong Kong?

Retinoic Acid is a prescription medication that can be prescribed by healthcare providers.

FAQs

Can Retinoic Acid cure my acne permanently? 

Retinoic Acid can significantly improve acne but may not permanently cure it. Continuous use as directed by a healthcare provider is necessary for sustained results. 

How long does it take to see results from Retinoic Acid?   

Improvement is often seen in 6 to 12 weeks of consistent use.

Can I use makeup over Retinoic Acid?

Yes, you can apply makeup over Retinoic Acid. However, ensure the treatment has fully absorbed into your skin before applying makeup.

Is Retinoic Acid safe to use every day? 

Yes, it is typically used daily at bedtime, but always follow the specific guidance of a healthcare provider based on your skin condition.